Wednesday 20 October 2010

primate experimentation and secrecy

backlar writes about keeping the testimony of the primate experimenters secret and confidential.

what if it against my ethics?

what if i have ethics?

maybe that puts me at a disadvantage to take biomedical ethics at PSU.


backlar writes:

"In order to maintain a 'safe place' in our classroom for each of us -- being
mindful of the principle of 'respect for persons'-- we will hold our conversations as
confidential in precisely the same way which we do when we work with other
bioethicists, clinicians, patients, family members when we conduct an
'Ethics Consult Service' where we address issues relevant to patients in clinical practice
or in the hospital. The 'principle' of respecting confidentiality is an essential
part of the practice of medicine.

Furthermore, we owe respect to our guest speakers. The clinicians,
researchers, and professors who so generously take time from their busy schedules to visit our class
and share their expertise with you well understand the importance of the work to which you aspire.
As our guests trust that their conversations with you and with each other will remain private and
confidential."

Tuesday 12 October 2010

international comparative bioethics


Since 2003, experimentation on great apes (chimpanzees, pygmy chimpanzees, gorillas, orangutans) and nine species of Gibbons have been banned in Sweden, but it is still permitted to use other primates for animal testing.
In Sweden, primates are used for vivisection experiments at the Institute for Infectious Disease Control (SMI) in Solna. The primates used are macaques that are imported from breeding facilities in China and Israel. Even though it is illegal to purchase primates caught in the wild, SMI has been found to have purchased wild apes on several occasions.


from
http://www.stoppaprimatforsoken.nu/in-english
regarding
swedish standards

SMIs experimentation on primates is very controversial. In the year 2000, Aftonbladet (the biggest evening newspaper in Sweden) carried the following headlines: “SMI banned from keeping primates” and “the animal cruelty has ended”. The background to this press attention was that SMI, since 1994, has not been abiding by rules and regulations stipulated in the Animal Cruelty Act. Furthermore, SMI had lied to the Department of Agriculture in regards to the size of the cages that housed the primates. The Department of Agriculture even went so far as to “question SMI:s competency in conducting any type of animal testing whatsoever”.
The greater majority of apes at SMI live in two meter high cages, about as small as three normal-sized closets. They are housed in pairs or in a group. A small number of individuals also have the possibility of getting some fresh air by being temporarily placed in an outdoor cage, but this cage is only available to primates being used for certain experiments.
One demand made by the Department of Agriculture, which would allow SMI to keep its permits to experiment on animals, was the daily training of primates for “cooperation” in the taking of test samples. To better facilitate the capture of the primates for anesthesia and test sampling, the primates are trained to “cooperate” using so-called “clickers” (the purpose is to train the primate to volunteer their own arm to be pricked with a needle in exchange for a reward). But SMI continues to capture primates with the help of a movable wall at the back of each cage that presses the primate up against the cage bars, restricting their movements.
SMI admits to not abiding by the demands of the Department of Agriculture.
EUPRIM-Net is a network of 8 European animal testing facilities that use primates and SMI is one of those facilities. The idea is that together, the 8 build a virtual primate center for the experimentation and breeding of primates.

for a comprehensive list of international primate testing sites and more about primate sourcing the the UC system and the AETA scroll down here:
http://www.indybay.org/newsitems/2010/06/19/18651256.php

animal welfare act violations, national primate liberation week, chattel

WHAT IS WRONG WITH OHSU?: SCREENING OF “CHATTEL”

SATURDAY OCTOBER 16TH, 7:00P

5TH AVE. CINEMA, 510 SW Hall St

“Chattel” is a documentary film about the animal research industry and the movements to abolish it.

The film will be followed by a discussion, facilitated by the Animal Defense League, on the current state of OHSU and the campaigns to stop its primate testing program.

Sponsored by the Student Animal Liberation Coalition- salcpsu@gmail.com

This event will be in conjunction with Animal Defense League's week of action against the Oregon National Primate Research Center, part of National Primate Liberation Week.
Over 70,000 primates (rhesus monkeys, baboons, squirrel monkeys, chimpanzees, etc.) are experimented on every year in the United States. Many thousands of primates are also imprisoned in labs for breeding and conditioning. Recent USDA statistics reveal that over 124,000 primates are held captive in U.S. laboratories.

Many of these primates experience horrible conditions. Recent government documentation has revealed primates dying of dehydration, starvation, hypothermia, heat stress, being boiled alive in cage washers, wasting diseases, hepatitis, encephalitis, and many other severe illnesses.

National Primate Liberation Week will take place October 16th – October 24th. Please help fight for the chimpanzees, rhesus monkeys, spider monkeys, marmosets, lemurs, squirrel monkeys, owl monkeys, and all the other innocent primates confined in laboratories. Help us end their abuse!

In Portland, we will be targeting OHSU's National Primate Research Center, which houses over 4,200 primates and has been fined for numerous USDA violations of the Animal Welfare Act.

sleepless due to concerns regarding ohsu

http://www.sourcewatch.org/index.php?title=Eliot_Spindel

4000 macaques now according to our guests the grey suited one

http://www.tobacco.org/news/121152.html

when i asked the grey-sited primate researcher about the nicotine experiments he at fist acted like he knew nothing of it.
i then said blandly, oh i read about it on the internet about four years ago.  then he assented as if well yes it were true.  or maybe he wasn't there.  maybe it wasn't his particular interest.
http://www.sourcewatch.org/index.php?title=Oregon_National_Primate_Research_Center

depression selfmutilation unaesthetisized ejaculation by electrical shock  by the techs
a method discovered through human torture

the video taken by ohsu employee matt rossell
watch the footage of a sick baby macaque at OHSU
in judy cameron's behavior studies




from ALF's website

Nova Will Stop Doing Business With Primate Products

By Michael J. Mooney
Tue, Sep. 14 2010
Broward/Palm Beach New Times
Nova Southeastern University in Davie will no longer do business with Primate Products, the controversial animal research facility in Doral, according to the Animal Rights Foundation of Florida .

After the release of several disturbing photos depicting monkeys with serious injuries, local activists approached university officials about Nova's relationship with Primate Products.
An administrator admitted the school has purchased monkeys from the facility for a research project funded by the National Institute of Health, says Don Anthony, ARFF spokesperson.
"They informed us that they will not be working with that facility in the future," Anthony says. Calls to Nova were not immediately returned.

"They've chosen not to be associated with the disturbing, bloody photos," Anthony says. "We're glad they came to this decision. There's no reason any research should be using live animals."

Last week, the USDA announced it will conduct a special investigation of Primate Products.

Anthony dismisses claims that animal research provides important scientific knowledge and leads to better medicines.

Animal rights advocates say 90 percent of universities in America no longer use live animals . "That includes Yale and Harvard," Anthony says. "If this type of research was so vital, like some people claim, everyone would be doing it. But they're not."

Local activists say they will continue protesting Primate Products -- and the home of President Donald Bradford -- until the facility closes down.

madness and civilization--foucault

http://en.wikipedia.org/wiki/Madness_and_Civilization

Monday 11 October 2010

for dorthea dix and antonin artaud

civil commitment process
police
hearing

dramatic decline

two people can go down to courthouse and begin the process of community investigation

county mental health

low level
standard of proof


probable cause
of mental illness

for civil court
http://en.wikipedia.org/wiki/Involuntary_commitment

if they believe that a person needs to be committed

they can be held in ERs for days


there are not enough beds

then they are transported in police cars far away---

we have knowledge increase
and decline of services


what irony


i ask if a family might try to frivolously incarcerate other family members
for personal distaste or purposes of a will (or other humiliations)

is there room for that in the law?  (by which i mean the oregon local law)

he says there is

there is
very little frivolous commitment

backlar shook her head at me.  i do not know for sure what it meant.

lots of protections for civil liberties
so says bloom

http://en.wikipedia.org/wiki/Dorothea_Dix

http://en.wikipedia.org/wiki/Antonin_Artaud

and the thorazine blues
http://en.wikipedia.org/wiki/Chlorpromazine

and chief bromden


there will be a new state mental hospital in the future

bloom psychiatrist forensic

attorney client privilege
defense attorney there
tell them

plenty of people
http://en.wikipedia.org/wiki/Insanity_defense

NGRI

how has columbine affected the evaluation process


MRIs, some brain disfunction on the tests

do not want to see inconsistency in the experts
psychologists
psychiatrists

virginia tech----violent video games---

why does PSU have violent video games

he played music
opera all night before the murders
kip kinkel


fascination with violent things

he tried to stab a kid

he could act normal and hide systems

his father did not believe in mental health
the stigma is strong

he stole the CD's
in bend---he and another kid were throwing snowballs at cars
the gun at school

anti-social behavior

the prosecution  blew up this . . .

commitment standard
http://psychservices.psychiatryonline.org/cgi/content/abstract/45/5/466

bloomj

ohsu
http://www.jaapl.org/cgi/content/abstract/34/4/534

http://ajp.psychiatryonline.org/cgi/content/abstract/144/7/847

http://www.jaapl.org/cgi/content/full/35/1/32

homocysteine and "schizophrenia"

http://www.ncbi.nlm.nih.gov/pubmed/16143442

http://findarticles.com/p/articles/mi_m0ISW/is_283/ai_n18744429/

http://www.nature.com/mp/journal/v11/n2/abs/4001746a.html

homocysteine pathways regarding

homocysteine hallucinogenic in effect---a toxic break down product which cannot be broken down without adequate b viatamins

and which has hallucinatory effects
http://www.bio.net/mm/toxicol/2004-November/003513.html

an old term

bloom agrees when i ask it that
schizophrenia will be outmoded as a term
and there will be a more adequate series of terms specific to the process

b vitamin therapies

that will eventually be broken down into othe

stress model

propensity as well as stress factors


abstract from:
http://www.nature.com/mp/journal/v11/n2/abs/4001746a.html


Elevated plasma homocysteine concentration has been suggested as a risk factor for schizophrenia, but the results of epidemiological studies have been inconsistent. The most extensively studied genetic variant in the homocysteine metabolism is the 677C>T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene, resulting in reduced enzyme activity and, subsequently, in elevated homocysteine. A meta-analysis of eight retrospective studies (812 cases and 2113 control subjects) was carried out to examine the association between homocysteine and schizophrenia. In addition, a meta-analysis of 10 studies (2265 cases and 2721 control subjects) on the homozygous (TT) genotype of the MTHFR 677C>T polymorphism was carried out to assess if this association is causal. A 5 mumol/l higher homocysteine level was associated with a 70% (95% confidence interval, CI: 27–129) higher risk of schizophrenia. The TT genotype was associated with a 36% (95% CI: 7–72) higher risk of schizophrenia compared to the CC genotype. The performed meta-analyses showed no evidence of publication bias or excessive influence attributable to any given study. In conclusion, our study provides evidence for an association of homocysteine with schizophrenia. The elevated risk of schizophrenia associated with the homozygous genotype of the MTHFR 677C>T polymorphism provides support for causality between a disturbed homocysteine metabolism and risk of schizophrenia.



more

Abstract

Homocysteine is a sulfur containing amino acid that has been widely investigated for its putative role in cardiovascular and neuropsychiatric disorders. It has been suggested that homocysteine has implications especially in young, male schizophreniapatients. In this prospective case-control study, we compared plasma homocysteine levels in a group of adolescent schizophreniainpatients (aged 14–21 years; n = 23) to normal healthy controls (n = 51). Mean plasma homocysteine levels were significantly higher in the patient group than in the control group (15.40 ± 2.00 and 9.78 ± 0.33 Î¼mol/L, respectively, p < 0.032). The difference was almost entirely attributable to the male schizophrenia subgroup (18.18 ± 5.65 in male patients vs. 10.31 ± 5.33 Î¼mol/L in female patients). The group × sex interaction was statistically significant (p = 0.0035). These data indicate that a subgroup of male adolescent schizophrenia patients has high homocysteine blood levels. The role of homocysteine in the pathophysiology of adolescent-onset schizophrenia merits further investigation.

joseph bloom from OHSU psychiatry

head of community psychiatry
in oregon
transcultural focus

indian native eskimo involvement with the law

more mentally ill people getting in jail services.
http://www.g4s.us/en-US/

today we have the lowest number of beds in the oregon psych system in 75 or 100 years


large numbers in the prison systems
1955---several hundred thousand people in state facilities---oregon OMG!!!!!!

bill sacks
professor emeritus
child psychiatry


back to bloom

first wave
psychotropic medications
1966
he finished his residency


the laws changed in the seventies

it became hard to civilly commit


current dates to 1873
1862

wave: decrease going in people
increase community services and they did not keep up with deinstitutionalization.
bleak care

two state
650 beds
oregon state salem and portland

eastern oregon state hospital
50 beds


mostly filled with court orde
incompetant to stand trial
sent to the hospital for the restoration of competancy

not guilty

by reason

70 geriatic
100 civilly committed

no voluntary payments in state hospital

state can run involuntary care


decrease in general hospital beds
more cash with non-mental care issues

very little care
pushes
by nature of the system
towards police and criminal justice

james otis (i mary eng met his family)
personality change in his personality change

more time by himself
depressed
did not seek resources

mother
inquiries how to involuntarily commit him

investigates civil commitment statute

he had a gun
traffic stop

he was killed by the police

the courts

http://www.oregonlive.com/portland/index.ssf/2010/06/post_20.html

http://blogtown.portlandmercury.com/BlogtownPDX/archives/2010/05/21/enough-is-enough-parents-of-aaron-campbell-and-keaton-otis-speak-near-tears

Former Director of Oregon Action Joanne Bowman graphically described Otis's death. "They shot him over 30 times and when they were done shooting him, they shot him with the beanbag and the taser and then they left his body in the street, uncovered, for six hours," said Bowman.


dr sack, guest speaker number two
courtroom and prison

106 years

attorneys did not go for a mental health defense

they thought that he might only get 20-40 years
they thought they had worked something out

he goes to mcclaren (juvenile jail system in oregon)
sack is the consultant and evaluator at the prison
works with him till he is 25

got him on therapy and medication
treatment is confidential---he is now in adult treatment
his sister is devoted and she has hired an attorney for an appeal

was kip kinkel understanding that he could make a decision about a state hospital defense
he thought a hospital would be worse than jail
it went to court
2 years ago

judge said no, so he is still in jail

less than positive outcome

case of kip kinkel

oren bolstad
called

killed his parents and went to springfield hospital

high profile case
national news

a year after littleton colorado shootouts

voices, hallucinations

telling him: you need to kill

his parents repeated the verbal abuse his parents issued
"stupid piece of sh*t"

see this link recounting the sack perspective as psychiatrist:

kip kinkel shoplifted nine inch nails
he identified with the lyrics

trent reznor sang about
"god damn these voices in my head"

he quoted this at school and got in trouble fro saying "god damn"

he was reluctant to take medicine
thought he was chipped and others had cameras in their glasses

it was very painful for orin bolstad

he tried prozac
orin bolstad
william sack

speaks of delusions:
as a necessary to dia-gnosis
schizo-phrenia
an archaic term
meaning split brain

which i think should be reformulated for greater acuracy---or more specific to what was not known of the neuroscience of cognition

i support

INDUSTRY LITERATURE
(pre-blogosphere)


(i was in productions of these with director bart whitman and bill siesser who played critical characters dysart and bromden  in the nineties at montgomery bell academy as a teenager----and was well avised)))))





i worked on a not guilty by reason of insanity case with los angeles attorney stephen schwartz in 2007 regarding a murder by a young man who murdered a clerk with a baseball bat at a convenience store.

we met with the family.

it was very formative.

this was prior to taking criminal law or administration of justice:police procedure at LACC .


bloom is the forensic psychiatrist
clinical diagnoses 

statute
you must know right from wrong to be guilty of murder

oregon insanity test
mcnaughten test---30 states

american law institute test---at tim e of crime by way of defect


lack substantial capacity to interpret the criminal content of the act
appreciate
test of volitional 


an hour after the shooting
another psychiatrist saw him

no ask about voices
strong feeling that he was psychotic

plea bargain agreed to this verdict

everything relates to the time of the crime


everything at the trial will relate to this crime
affirmative defense to the charge

yes i did this
but was insane at the time



interests at heart---hippocratic oath

patient autonomy

abrogation of their duty

not a trick case

honesty demanded

when physician is trying to protect a patient from a terminal illness's psychological effects----

discussion question
issues
relevant to
profound depression


people are very fragile
certain aspects make him a  delicate person

her son: how easily he feels paranoid as if someone is going to harm him
even people that he trusts


he is not happy with his clinician

george saslow---musician
http://ohsu-hca.blogspot.com/2006/09/in-memoriam-george-saslow.html

tying papers together
excerpt
rights as moral intersests

clinician abrogates rights

liability devastating


what you would hope for clinician to be a kind enough friend
clear he needs to get there


not easy

ethics and privacy and private torture chambers

http://en.wikipedia.org/wiki/Foreign_Intelligence_Surveillance_Act

http://www.ncsl.org/IssuesResearch/TelecommunicationsInformationTechnology/ElectronicSurveillanceLaws/tabid/13492/Default.aspx

http://ohsr.od.nih.gov/guidelines/nuremberg.html

it is very interesting to me that PSU legal team is now aware that i bambuser.com videoblogged the primate researcher's very interesting discussion of his research.  i posted a link up at indymedia because many people do not have a chance for a college education nor do they have the privilege of animal researchers speaking to them about their work.

that i have poured over my animal law book is of no concern to anyone.  that i have worked with many animal rights groups is known at least to myself.

but what i am more concerned about is the flow of information being kept from humans.
the abrogation of FISA or local oregon free speech restriction or the AETA seem very small compared to the torture i have experienced and that i have heard of at OHSU.

i saw the macaques and they begged me for release.
they banged on the wall.
they grasped their babies in fear.
i just personally cannot imagine a career in animal testing.

but maybe OHSU is hiring.

patricia backlar is extremely gracious and wonderful and spoke to me and wants me to not videoblog any more of her classes.

the breach of trust, in the lack of permission granted broadcast of their lecture---the anonymous OHSU primate experimenters--- . . . .

my goal aside from sharing the infamy of OHSU with the international public was to broadcast my misery in hearing of the animal experimentation

i told patricia backlar, my heart raced, my hands shook, my knees shook, perhaps i should have walked out.

i do not like being around people that make me uncomfortable, and monkey-torturers actually do make me extremely uncomfortable.

in a sense i wish patricia asked us if we were ready for such an inconsiderate displace of cruelty, speciesism, torture, and arrogance.

i cannot believe how disrespectful these fellows were in the way they spoke of animals.

i have an audio file in addition to the bambuser.com/maryeng1 files.

should i be a part of OHSU secrecy?

that is a little too much for me to ask of my conscience.

this is an ethics class after all.
her son has schizophrenia, a concert pianist
i am so glad my mother does not call me schizophrenic!!!!  she has translated or transcended such labels

maybe he needs some b vitamins to break down the homocysteine implicated in this way of humans discussing humans
http://findarticles.com/p/articles/mi_m0ISW/is_283/ai_n18744429/
so says patricia backlar
http://www.amazon.com/Family-Face-Schizophrenia-Patricia-Backlar/dp/0874777909

http://bambuser.com/channel/maryeng1

Tuesday 5 October 2010

AETA and OHSU primate testing and Zoos clearly seemed cruel to me as a child

http://www.organicconsumers.org/patent/glowingmonkey.cfm

http://portland.indymedia.org/en/2010/10/402828.shtml

http://bambuser.com/channel/maryeng1/broadcast/1063905

unbelievable

crassness

my heart was racing to hear of the torture of these animals
and to see the pictures the fellow brought in

and to hear him get really foggy on the nicotine experiments on pregnant primates.

he sat beside me.  it was i who felt like i was torturing him with the clarity of my questions about who is legal representation and pharmeceutical litigation.

poor thing.

i wanted to tell him i liked his grey suit.  it looked super prada minimalist.
fashion for animal torturers.

i told him i saw the facility.

i didnt tell him what the animals clearly communicated:
we are in hell
help us out.

they banged on the walls!!!

written for anthro last january:

Visiting the zoo reminded me of a surprising experience I had involving the Rhesus Macaque, a popular animal for animal research.  When I was in Portland Oregon, a friend who worked for OHSU unwittingly took me by the OHSU macaque pen.  He did not know how well I like animals.  We climbed to the top of a platform.   It was my very first time as an adult to see non-human primates.  As a child I found zoos to be traumatizing. I remember being bewildered at the at the Washington D.C. Zoo. Even as a child I could see that the gorillas behind plexiglass were in obvious distress.  The gorillas banged on the glass and lumbered around as though depressed.  I thought adults were not so smart for thinking they were entertaining me, because it was like a nightmare.
The macaques (maybe fifty in number or more)  were in a corrugated metal pen at least 100x100 feet, with piles of bananas around and wheels to run on.  There were little huts to hide in.  It was raining heavily and very muddy.  The mothers held their babies protectively as if they were afraid I would take their young.  Some actively called out or made demonstration of aggression or fear.  Some were oblivious. I began to imitate their speech sound (a clicking sound) and focused on communicating solacing tones and energy.  Some began to put their fingers at and underneath the base of the corrugated metal.  They started tapping and banging on the metal.  When we walked down the platform stairs and along the opposite side of the compound, they put their fingers underneath the wall following the sounds of us walking. There fingertips were reaching out and others continued banging on the walls. Obviously they desired release.  I kept talking sympathetically to them, and I think we very clearly communicated quite a lot of information.
I began to the research what types of tests are run there and what alternatives are available.  The test most commonly cited by opponents is nicotine injection for pregnant mothers. The last I heard, the suburb where the facility was besieged by persistent activists and irritated at the stench so much so that neighbors united against the nuisance factor of it.  So plans were being made to take the primate lab further out from the city.  A fellow, Matt Rossel of (non-violent group) In Defense of Animals had worked undercover for OHSU as a lab tech following a stint undercover at a mink farm.  I heard him speaking one day on the radio about the stresses on the legs and feet of circus elephants.
I felt strangely privileged to see the macaques.
I then found lots of disturbing footage from labs in Europe and hubbub regarding the Huntington Labs, the Shac 7, and the stress disorders primates undergo.  This was 2006.  The Patriot Act had recently been passed and with it what is known as the Animal Enterprise Terrorism Act, which effectively makes information distribution criminal.  Currently some kids are being hassled over a flyer, the premise being that disseminating information that might disrupt an animal enterprise is a terrorist activity---this will be a very interesting new area for human rights law, free speech, and animal law.  The international activist web ring “Indymedia” was at that time put in the FBI's terrorist watch group.  This Portland version of the website has a very active animal page regarding fur store protests and OHSU primate testing activism.
I remember one day hearing of a suicide of animal activist in jail that was thought to be a murder.
Portland's activist community is quite vibrant, with law students (many enviro law from Lewis and Clark) filming all activist activities for future litigation in the event of police brutality.  A nice foundation, The Northwest Center for Constitutional Law was established after a $800,000 suit victory regarding a 2003 George Bush visit protest at which police used pepper spray in a baby's face.

Monday 4 October 2010

ethics at OHSU?



protocols approved by IRC review board
community member

for what is going on

they all have a conflict of interest
helps as a cap

nonscientist

that consent forms
make sense to a non-scientist

compensation it is not unethical to pay someone 

acc to IRB

too much is coercive

lots of impovrished people on medicare or medicaid
come to OHSU for studies

cosmetic procedure in beverly hills

what are you sking a subject to do

simple blood draw
50$ for blood
not coercive

500$ would be
dependent

craigslist

upper income bracket sliding scale

study the rich!!!

socioeconomic levels

IVF fertility
underpaid


6 yrs

undue inducement

hazardous to women

the nobel prize today

washington universitytissue samples
washington university purposes

the patients no longer had right to 

nobody is talking about anarchy power or property rights
or rights theory

common rule
ethical vacuum.

regents cell line from a sample

commercialization

intellectual property of subjects

board of regents case

UCLA follow up care
no opportunity to say no.

the immortal life of

times literary supp

opp view

very interesting to speak to the grey suited primate researcher
check legal team here:

he didnt know about the seroquel lawsuit

literally a primate surgeon specialist working on sedated macaques.
hmm

human subjects research


News: Patricia Backlar appointed to OHSU Stem Cell Research Oversight Committee


patricia has brought in from OHSU

chief integrity officer

human subjects research

ethics

contemporary cases

http://www.pdx.edu/news/patricia-backlar-appointed-to-ohsu-stem-cell-research-oversight-committee

animal research has more laws
4x

human subjects can exit
vote with feet

cancer bone marrow

http://ohsr.od.nih.gov/guidelines/nuremberg.html
http://en.wikipedia.org/wiki/Nuremberg_Code

http://en.wikipedia.org/wiki/Josef_Mengele

1932 tuskegee syphilis
http://en.wikipedia.org/wiki/Penicillin
sir alexander fleming
1919

pathogenesis of syphilis

federal regulations
http://ohsr.od.nih.gov/guidelines/belmont.html

too late for tuskegee

too late for guatamala

belmont report
http://ohsr.od.nih.gov/guidelines/belmont.html
non-malefeasance
beneficence

FDA
http://nihroadmap.nih.gov/clinicalresearch/

http://www.fda.gov/

http://www.aboutlawsuits.com/seroquel-951/

http://www.coreynahman.com/atypical-antipsychotic-lawsuits.html

backlar recommends
http://bioethics.net/mt/mt-search.fcgi?tag=Alta%20Charo&IncludeBlogs=1
http://www.law.wisc.edu/profiles/racharo@wisc.edu

http://en.wikipedia.org/wiki/Alta_Charo

SSRI's

for children
http://www.safecosmetics.org/

can restrict
via audit
http://www.hhs.gov/ohrp/

animal protections more extensive

human subject research without federal funding

practical---hard to do
publish
practice

or get approved or licensed

private practice research
split

sued for malpractice
exceeded malpx insurance

IRB
institutional review board
defined

common rule
ir

5 members
no conflict of interest

must have a nonscientist
reflect the nonscience coming t us

every subspecialty coming to us

state mental hospital

high rate of suicide
FDA approved for kids based on adult only research

they were dissuaded from research on kids

take limited testexpand
effects fatal

same thing with overprotecting women of childbearing age
no tests then
damage to women
HIV
cardiovascular

FDA 30 yrs out of sync

the common rule

psu primate research OHSU at PSU

palliative care

PI

veterinary staff

http://www.lclark.edu/law/law_reviews/animal_law_review/

stakeholders

future humans

taxpayers

other primates

primate research in oregon

http://www.shac.net/

22 yrs life span

http://en.wikipedia.org/wiki/Animal_Enterprise_Terrorism_Act

http://www.lclark.edu/law/centers/animal_law_studies/

primate researcher fm OHSU comes to PSU

animal welfare concerns

posted signs
welfare concerns posting

IACUC

anonymous reports

supervisors may view employee's concern as a difficult employee rather than considering seriously

reluctant to cause problems
traditional

put the conflict on to a slide

healthy conflict  investigators want to solve big problems of medicine

relief of human suff
professional success

scientific protocols to a t

SHAC
AETI

huntington
suffering matters
do no harm

propaganda of placation and defense for the PSU future

conflict of interest
nice grey suit
a surgeon

OHSU primate researcher visits PSU

we dont handle them nonsedated

they revenge

rhesus macaque

http://en.wikipedia.org/wiki/Rhesus_Macaque

22-25 yrs in captivity

matrilineal

ONPRC
oregon national primate research center

SIV similar to HIV
SIV HIV hybrid

govt

usda
PHS

scientists
AALAS
AAALAC

forces the  an welf act---usda
ILAR

animalcentric organizations
humane society

health care consumers

british cruelty to a

iacucnimals act 1876 british

nuremberg code has to be based on animal expiramentation

surrogate

http://www.iacuc.org/

gary is the master

4000 monkeys

each is 4000 a pop

genetic
2000 mice genetically engineered high$ mice

iacuc
http://www.iacuc.org/aboutus.htm


food animals
a curious concept to a vegan
ethics of guatemala experiments

http://www.thetakeaway.org/2010/oct/04/

norway study
clearly acknowledged of dangers of untreated syphilis

http://www.npr.org/blogs/health/2010/10/01/130266301/u-s-apologizes-for-medical-research-that-infected-guatemalans-with-syphilis

speaker:
public state health officer
anthrax attacks
state health department
dept. of human services
new: oregon health authority
launches next july 2011

social services not public health

all of these things affect health

surveillance info is dirty in the sense that it is chaotic but it is useful?

BMI obesity
state govt.
state medicaid
purchasing programs
it turns out the state puchases about 25% health insurance
flu in oregon

beyond H1N1

mmwr

morbid mortality weekly report
overdue for a pandemic

march 2009
near dead november 2009

flu as a pathogen
it changes every year
every 30-50 yrs it changes a lot

and we are

WWI

sequeli occurred htereafter

young hit hard
flu pandemic
in 1918

soldiers hit very hard

fined

by late aft dead

media attention
first press conference
H1N1

bruce goldberg
gary oxberg

epidemiologist by training
2 yr fellowship in applied graphs
the landscape changing
getting ready to
camera

how do you communicate to the public
very scared
weeks in late fall
peak feb march week 9  peak in april

things exploded in the fall

kids a great vector for communicating disease
purple high

patient privacy v. statistics gathering

portability and accountability act
HIPAA
http://en.wikipedia.org/wiki/Health_Insurance_Portability_and_Accountability_Act

for pub health purposes this can be shared

yet we take care to safeguard info

reporting system bases on willingness

AIDS collection
name to code

prior anonymous

at least then some demographic reporting good

data stndpt  need to link reports
multiple viral load tests with AIDS patients.

service
hooked up to services
balancing act

medical experiments #8 neuberger basement

we are speaking of tuskegee
and nuremberg code

nazi doctors
mangle

eichmann in jerusalem

http://en.wikipedia.org/wiki/Unit_731

http://en.wikipedia.org/wiki/Tuskegee_syphilis_experiment


research protocol
writing later on in the course

not in this term

just take a case

which was agood example

whether we can train the example

that ties this together
textile business in germany

rise of chemistry understanding

thereapies
the medical profession
fluorished to a great extent in germany and france
and the

german doctors in the USA were more valued bc of background

le main salle

we all have dirty hands
tuskege

cookie time!!!

with the amazing Patricia Backlar